I reckon every bit helps as lighter followers means that is less weight the valve spring has to push back against the cam lobe. When the engine has 24 milliseconds or less to close a valve from fully open to closed @ 10000 rpm, the amount of spring pressure available and the mass of the valve train components including cam follower determines how fast the valve train can close. F=ma.
Its just a question if the titanium ones are sufficiently lighter than the Motorsport ones to justify what will be at least $65 Oz per lifter