Drift.
I evaluated a Detroit Locker in a Falcon Van for about six months & wrote a monthly report on all trials. Even with the ability to unlock when necessary [diferential action] the front tyre life was significantly reduced from the average in my fleet of about 40,000k, to under 30,000k I think replacements were fitted at about 28,000k. In all fairness, the life of the second set of front tyres was better at 32.000k as i had learned to be more gentle with it. The "gentle" technique would have no beneficial effect on tyre life with a locked diff.
I drove it for over 50,000k & even the rears lasted for only about 32, to 34,000k. I was driving normally, with some experimental off-road use. [The real reason for the trial] In the hands of an "enthusiast" tyre life was regarded as being somewhat less.

A locked diff would ensure that tyre life was reduced even further, & when you need to get the best from your motoring dollar, this is not the way to do it. In normal fleet use, i was getting 50, to 55,000K from the tyres on a Falcon sized car, or about one set of tyres every ten months on average.

From 55,000 down to 28,000k for front tyres seems to me to be significant, although it must be understood that my Falcon wagon had radial highway tyres, & the evaluation van had a mud & snow type tread on it's radials for off road use, & this would affect the figures to a degree.