I'm telling you, if you want something extreme the turbo Buick 3.8L V-6 would give you more than any 1UZFE could dollar for dollar. These engines are easy to get 500+ hp from. If you're worried about weight I would suggest a browse at TA Performance they make a super strong and redesigned all aluminum block and heads for these engines that would substantially cut down the weight compared to a V-8. If you're really serious about building something "extreme" I hope you have some $$$ to spend. You'll need chassis reinforcement, safety equipment, and a bullet proof drive line if you plan on dragging it at all. Don't forget about breaking parts and having to replace them. I can't imagine a Supra gearbox is very affordable/common nor any parts for the 1uz-fe which doesn't have barely any aftermarket support, especially in the US. And if you want to drag race it and be consistent/competitive you'll never get there with a manual transmission. That's my .02