battery - cable - isolator - cable - starter post - accessories running off starter post.

CB is just another point of failure, just make sure that the cable is well installed/protected where it passes any sharp edges.

Also, are you wiring the alternator thru the isolator (you can get special isolators that allow this)? If you don't you will find the car will continue running when you open the isolator (i.e. disconnect the battery) and possibly damage the alternator.. When the isolator is opened, the car should stop immediately to pass scrutineering.