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Throttle response. The fuel has to go though an awfully long and tortured path to get from the carb to the cylinders with a draw through. With a blow through, the throttle is right where the engineers put it in the first place, so throttle response should be the same as stock. Then there are the cold starting issues, but that's not a performance argument.
I guess once it is on boost, the performance difference is probably negligible, assuming the blow through isn't using an intercooler.