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The motors won't be a problem, late model bikes can do big K's no problems, it is the tranny/clutch that is affected by the extra weight a car carries.
My bike has done 50k in 4 years, no problems whatever, this is a 140hp motor that rev's to 9.5k and sits at 4.5k on the freeway all day long..
This is part of the reason I'd recommend a larger engine, bikes like the Hayabusa, GSX1400 and ZX14 have much more solid gearboxes than a lot of the 600cc (etc) bikes which are built to save every gram possible.
On the topic of motors, you also need to remember that having been designed for use at 350-400kg (220kg + rider + pillion) the motors will need the CR or tune revisited to save it detonating.
The larger motors also allow better performance. The big bikes run 140-150mph at the drags, so if you can get a car down to say 600kg and do a few performance mods (exhaust system, cams, etc) you should still have something capable of running 11s.
Using the argument that you save $1-2k on the initial motor purchase is a little misguided - you're about to spend a small fortune setting up the rest of the car so to cut a corner like that you end up with a poor result and lots of 'wasted' money.